Recent Advances (published since 109th Congress’s stem cell votes) in Adult Stem Cell Research and Other Alternatives to Embryonic Stem Cell Research

June 2006 – present

OVERALL SUCCESS

• “Adult cells are behind much of stem cell success so far,” Milwakee Journal Sentinel, September 2, 2006, www.jsonline.com/story/index.aspx?id=489953&format=print
• “Review: Ex Vivo Engineering of Living Tissues with Adult Stem Cells,” Tissue Engineering, October, 2006, www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=170 64229

ADULT STEM CELL VERSATILITY

• “Adult stem cells are touchy-feely, need environmental clues,” EurekAlert, August 24, 2006, www.eurekalert.org/pub_releases/2006-08/uop-uop082306.php
• “Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors,” Cell, August 25, 2006, www.cell.com/content/article/abstract?uid=PIIS0092867406009767&highlight=Yamanaka
• “Adult Stem Cells Can Become Muscle,” The Daily Californian, November 1, 2006, dailycal.org/printable.php?id=22084
• “U of MN adult stem cell research shows promise for transplant therapies,” EurekAlert, January 15, 2007, www.eurekalert.org/pub_releases/2007-01/uom-uom011207.php
• “Fate of Bone Marrow Stem Cells Transplanted into the Testis,” The American Journal of Pathology, March 2007, ajp.amjpathol.org/cgi/content/abstract/170/3/899
• “Type of Stem Cell Found to Reside in Transplanted Lungs,” eMaxHealth, March 10, 2007, www.emaxhealth.com/cms?m=show&opt=printable&id=10162

STEM CELL SOURCES

• “Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells,” Proceedings of the National Academy of Sciences, June 12, 2006, www.pnas.org/cgi/doi/10.1073/pnas.0604850103
• “Fat Stem Cells Being Studied As Option For Breast Reconstruction,” Medical News Today, October 30, 2006, www.medicalnewstoday.com/printerfriendlynews.php?newsid=55275
• “Penn Prof. Makes ‘Hair’-Raising Stem Cell Discovery,” The Evening Bulletin (Philadelphia), November 17, 2006, www.zwire.com/site/index.cfm?newsid=17480108&BRD=2737&PAG=461&dept_id=576361&rfi=8
• “Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles,” The American Journal of Pathology, December 2006, ajp.amjpathol.org/cgi/content/abstract/168/6/1879?maxtoshow=&HITS=10&hits=10&RESUL TFORMAT=&author1=Yu&titleabstract=Isolation+of+a+novel+population+of+multipotent+adult+stem+cells+from+human+hair+&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
• “Stem cells found in adult hair follicles may provide alternative to embryonic stem cells,” EurekAlert, December 11, 2006, www.eurekalert.org/pub_releases/2006-12/mcow-scf121106.php
• “Don’t Surrender Any More Teeth to the Tooth Fairy,” Scientific American, December 26, 2006, www.sciam.com/print_version.cfm?articleID=C0956FBC-E7F2-99DF-3DF2604378A72C61
• “Isolation of amniotic stem cell lines with potential for therapy,” Nature Biotechnology, January 7, 2007, www.nature.com/nbt/journal/v25/n1/abs/nbt1274.html
• “Bioengineer Advances Survival, Promise of Adult Stem Cells,” Science Daily, February 28, 2007, www.sciencedaily.com/releases/2007/02/070227121355.htm
• “Liposuctioned fat stem cells to repair bodies,” European Science Foundation (Press Area), February 22, 2007, www.esf.org/esf_pressarea_page.php?print=1&language=0&section=6&year=2007&newsrelease=165
• “Liposuctioned fat stem cells to repair bodies,” European Science Foundation (Press Area), February 22, 2007, www.esf.org/activities/eurocores/news/ext-news-singleview/article/liposuctioned-fat-stemcells-to-repair-bodies-60.html

CORD BLOOD

• “States seek to save umbilical cord blood,” Stateline.org (Pew Research Center), August 2, 2006, www.stateline.org/live/printable/story?contentId=131281
• “State expands storage for stem-cell-rich blood,” North Jersey Media Group, Inc., October 18, 2006, www.northjersey.com/print.php?qstr=ZmdiZWw3Zjd2cWVlRUV5eTcwMDY3ODkmeXJpcnk3Zjcx N2Y3dnFlZUVFeXk1
• “Stem cell transplant: a ray of hope for thalassemic children,” The Hindu, October 26, 2006, www.thehindu.com/2006/10/26/stories/2006102614470200.htm
• “Cytotherapy Report Confirms BioE Stem Cell First Human Cord Blood Stem Cell to Differentiate into Lung Cell,” BioE News Release (St. Paul, MN), November 1, 2006, www.bioe.com/stream_document.aspx?itemID=973&parentID=971
• “New Use of Cord Blood to Treat Childhood Leukemia Study,” Yahoo News, January 5, 2007, www.cordblood.com/cord_blood_news/stem_cell_news/autologous_leukemia.asp
• “First Israeli saved from acute leukemia by umbilical cord blood from two separate births,” Jerusalem Post, February 12, 2007, www.jpost.com/servlet/Satellite?cid=1170359842760&pagename=JPost%2FJPArticle%2FPrinter
• “The miracle of cord blood,” Detroit News Online, March 7, 2007, www.detnews.com/apps/pbcs.dll/article?AID=2007703070398&template=printart
• “The miracle of cord blood,” Detroit News Online, March 7, 2007, www.detnews.com/apps/pbcs.dll/article?AID=2007703070398&template=printart

BONE/CARTILAGE

• “Gene Silencing Directs Muscle-derived Stem Cells to Become Bone-forming Cells,” Medical News Today, June 1, 2006, www.medicalnewstoday.com/medicalnews.php?newsid=44400
• “One-Off Treatment to Stop Back Pain – Using Patients’ Own Stem Cells,” The University of Manchester Web site, December 4, 2006, www.manchester.ac.uk/aboutus/news/display/index.htm?id=86105
• “Aussie stem cell trial wins US approval,” The Age (Australia), December 20, 2006, www.theage.com.au/news/National/Aussie-stem-cell-trial-wins-USapproval/ 2006/12/20/1166290605626.html
• “Stem cells revolutionize spinal surgery,” Victoria Advocate (Texas), February 3, 2007, www.thevictoriaadvocate.com/328/story/23340.html
• “Case Study Reports That Orthopedic Trauma Surgeon Injects Adult Stem Cells Derived From the Patient’s Own Marrow Into Her Broken Legs, Which Had Not Healed by Seven Months Post-Injury – Instead of Open Surgery,” Yahoo Finance, February 8, 2007, biz.yahoo.com/iw/070208/0213099.html?printer=1
• “Healing Bone with Stem Cells,” Technology Review (Published by MIT), March 7, 2007, www.technologyreview.com/printer_friendly_article.aspx?id=18274

BRAIN DAMAGE

• “Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington’s disease,” Experimental Neurology, June 2006, www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16626705&query_hl=3&itool=pubmed_DocSum
• “Researchers Find Healing Potential in Everyday Human Brain Cells,” Newswise, August 16, 2006, www.newswise.com/p/articles/view/522823/
• “Scientists spur growth of adult brain stem cells,” MSNBC (Reuters), November 14, 2006, www.msnbc.msn.com/id/15720021/print/1/displaymode/1098/
• “An appointment with chance,” The Economist, November 30, 2006, www.economist.com/science/PrinterFriendly.cfm?story_id=8348729
• “Cells’ Capability in Mouse Brain Tissue Repair Revealed By UCSF Stem Cell Study,” Medical News Today, December 21, 2006, www.medicalnewstoday.com/printerfriendlynews.php?newsid=59133
• “Scientists produce neurons from human skin,” EurekAlert, February 22, 2007, www.eurekalert.org/pub_releases/2007-02/ul-spn022207.php

CANCER

• “Catholic Priest’s Adult Stem Cell Donation Saves Kentucky Woman’s Life,” LifeNews.com (Kansas City, MO), June 29, 2006, 66.195.16.55/bio1580.html
• “Cancer-Killing Invention Also HarvestsStem Cells,” Medical News Today, January 8, 2007, www.medicalnewstoday.com/printerfriendlynews.php?newsid=60251
• “Researchers first to map gene that regulates adult stem cell growth,” EurekAlert, January 14, 2007, www.eurekalert.org/pub_releases/2007-01/uok-rft011207.php
• “A new hope for cancer treatment: ‘U’ researchers find stem cells that cause tumors,” Michigan Daily, February 2, 2007, www.michigandaily.com/home/index.cfm?event=displayArticlePrinterFriendly&uStory_id=c5489b59-d0ef-43f2-8597-66a769ac3a1e

DIABETES

• “Stem cells may help Bergen boy fight diabetes,” NorthJersey.com (North Jersey Media Group Inc.), August 18, 2006, www.northjersey.com/page.php?qstr=eXJpcnk3ZjcxN2Y3dnFlZUVFeXkzJmZnYmVsN2Y3dnFlZU VFeXk2OTc3MTcx
• “International Trial of the Edmonton Protocol for Islet Transplantation,” New England Journal of Medicine, September 28, 2006, content.nejm.org/cgi/content/full/355/13/1318?firstpage=1318&volume=355&sendit=GO&searchid=1&FIRSTINDEX=0&volume=355&firstpage=1318&resourcetype=HWCIT
• “Insulin Stem Cells Hold Hope for Diabetes Treatment,” Forbes, November 7, 2006, www.forbes.com/forbeslife/health/feeds/hscout/2006/11/07/hscout535944.html
• “Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD scid mice,” Proceedings of the National Academy of Sciences (PNAS), November 14, 2006, www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17088535
• “AmCyte Presents Promising Adult Stem Cell Data at 7th Annual Rachmiel Levine Diabetes and Obesity Symposium,” Genetic Engineering News, November 9, 2006, www.genengnews.com/news/bnitem.aspx?name=8531775&child=4&taxid=39
• “Researchers Make Stem Cell Breakthrough,” The Korea Times, January 23, 2007, times.hankooki.com/lpage/tech/200701/kt2007012317475111810.htm
• “Diabetes repair ‘occurs in womb’,” BBC News, January 23, 2007, newsvote.bbc.co.uk/mpapps/pagetools/print/news.bbc.co.uk/2/hi/health/6286997.stm
• “WnT signaling regulates pancreatic beta cell proliferation,” Proceedings of the National Academy of Sciences (PNAS), Advance Online Publication April 2, 2007, www.pnas.org/cgi/content/abstract/0701509104v1

EYE/EAR

• “Bone Marrow May Restore Cells Lost in Vision Diseases,” Science Daily (University of Florida), June 8, 2006, www.sciencedaily.com/releases/2006/06/060608225650.htm
• “Eye experts showcase new treatments for glaucoma,” ABC Sydney, November 7, 2006, www.abc.net.au/news/items/200611/1783265.htm?sydney
• “Retinal repair by transplantation of photoreceptor precursors,” Nature, November 9, 2006, www.nature.com/nature/journal/v444/n7116/abs/nature05161.html

HEART

• “Researchers grow human heart tissue from stem cells,” ABC Online, June 7, 2006, www.abc.net.au/worldtoday/content/2006/s1657710.htm
• “Stem Cell Trials Show Sustained Heart Function Improvement,” Medical News Today, September 21, 2006, www.medicalnewstoday.com/medicalnews.php?newsid=52366
• “Cultured autologous stem cell trials show sustained heart function improvement,” Managed Care Business Week, October 17, 2006, www.newsrx.com/article.php?articleID=365417
• “Injecting Patient’s Own Stem Cells Treats Severe Coronary Artery Disease,” Medical News Today, October 24, 2006, www.medicalnewstoday.com/printerfriendlynews.php?newsid=54836
• “Using the Body’s Own Stem Cells to Grow New Arteries,” KGO-TV / ABC-7 (San Francisco), November 12, 2006, abclocal.go.com/kgo/story?section=edell&id=4754901&ft=print
• “Adult Pig Stem Cells Show Promise in Repairing Animals’ Heart Attack Damage,” Johns Hopkins University Web site, November 13, 2006, www.hopkinsmedicine.org/Press_releases/2006/11_13_06.html
• “Amniotic Stem Cells Offer Hope Against Congenital Heart Defects,” Washington Post, November 14, 2006, www.washingtonpost.com/wp-dyn/content/article/2006/11/14/AR2006111400889_pf.html
• “Potential Source of Stem Cells for Heart Repair, Other Uses Found in Fat of Elderly, Chronically Diseased Patients: Presented at AHA,” Doctor’s Guide, November 17, 2006, www.docguide.com/news/content.nsf/NewsPrint/852571020057CCF685257229005A86CB
• “Adult Heart Cells Learn to Heal,” Medical News Today, November 20, 2006, www.medicalnewstoday.com/printerfriendlynews.php?newsid=57088
• “U of M Finds Cell in Adult Heart with Embryonic Stem Cell Capability,” Academic Health Center at the University of Minnesota, January 18, 2007, www.ahc.umn.edu/print/news/releases/heartcell011807/home.html
• “Desperation leads to one last gamble in overcoming heart failure,” Orlando Sentinel, January 28, 2007, www.orlandosentinel.com/news/custom/science/orlstemcell2807jan28,0,1745635.story?coll=orl
• “Stem cells from fat transplanted into heart,” MSNBC (Reuters), February 6, 2007, www.msnbc.msn.com/id/17007196/print/1/displaymode/1098/
• “Heart patients head to Bangkok for life-saving stem cell treatment,” Yahoo News (United Kingdom), February 13, 2007, uk.news.yahoo.com/13022007/323/heart-patients-head-bangkok-life-saving-stem-celltreatment.html
• “M.D. Anderson moves forward in heart repair research,” Houston Business Journal, February 15, 2007, masshightech.bizjournals.com/masshightech/othercities/houston/stories/2007/02/12/daily66.ht ml?t=printable
• “‘Sticky’ Proteins Fuse Adult Stem Cells to Cardiac Muscle, Repairing Hearts,” Newswise, February 15, 2007, www.newswise.com/p/articles/view/527347
• “‘Sticky’ Proteins Fuse Adult Stem Cells to Cardiac Muscle, Repairing Hearts,” Newswise, February 15, 2007, www.newswise.com/p/articles/view/527347
• “FDA Approves Phase 1 Stem Cell Research Therapy for Congestive Heart Failure,” PRLog – Online Press Release Service, March 25, 2007, www.prlog.org/10011668-fda-approves-phase-1-stem-cell-research-therapy-for-congestive-heartfailure.html
• “Osiris’ Adult Stem Cells Help Heart Attack Patients in Study,” Bloomberg News Service, March 25, 2007, quote.bloomberg.com/apps/news?pid=20670001&refer=&sid=a_YZBRXSFiKs
• “Adult Stem Cells Help Heart Attack Patients,” Voice of America News (Washington), March 27, 2007, www.voanews.com/english/2007-03-27-voa26.cfm?renderforprint=1
• “British team grows human heart valve from stem cells,” The Guardian (UK), April 2, 2007, www.guardian.co.uk/print/0,,329765220-110418,00.html

IMMUNE SYSTEM (Multiple sclerosis, lupus, etc.)

• “Stem Cell Treatment Eliminates Lupus,” ABC7/KGO-TV/DT (San Francisco), June 5, 2006, abclocal.go.com/kgo/story?section=edell&id=4238935&ft=print
• “Adult stem cells in the treatment of autoimmune diseases,” Rheumatology, October, 2006, rheumatology.oxfordjournals.org/cgi/content/abstract/45/10/1187
• “Stem cell treatment helps former police officer,” The Intelligencer (Philadelphia), October 24, 2006, www.phillyburbs.com/pb-dyn/news/113-10242006-731427.html

KIDNEY/LIVER

• “Isolation and Characterization of Multipotent Progenitor Cells from the Bowman’s Capsule of Adult Human Kidneys,” Journal of the American Society of Nephrology, August 2, 2006, jasn.asnjournals.org/cgi/content/abstract/17/9/2443?maxtoshow=&HITS=10&hits=10&RESUL TFORMAT=&author1=Sagrinati%2C+C&fulltext=kidneys&searchid=1&FIRSTINDEX=0&sortspec =relevance&volume=17&firstpage=2443&resourcetype=HWCIT
• “British scientists grow human liver in a laboratory,” Daily Mail (United Kingdom), October 30, 2006, www.dailymail.co.uk/pages/text/print.html?in_article_id=413551&in_page_id=1770
• “Stem Cells Speed Growth of Healthy Liver Tissue,” ScienceDaily, March 28, 2007, www.sciencedaily.com/releases/2007/03/070327094518.htm

MUSCULAR DYSTROPHY

• “Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs,” Nature, November 15, 2006, www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&list_uids=17108972&cmd=Retrieve&indexed =google
• “Human adult stem cells regenerate muscle,” United Press International, February 15, 2007, www.upi.com/NewsTrack/Science/20070215-024231-4646r/

PARKINSON’S DISEASE

• “Stem Cell Treatment Proven to Reduce Parkinson’s Symptoms,” Medical News Today, October 25, 2006, www.medicalnewstoday.com/printerfriendlynews.php?newsid=54956

SPINAL CORD

• “Olfactory Mucosa Autografts in Human Spinal Cord Injury: A Pilot Clinical Study,” Journal of Spinal Cord Medicine, 2006, www.apssci.org/pdf/olfactory.pdf
• “Bone marrow stromal cells can achieve cure of chronic paraplegic rats: Functional and morphological outcome one year after transplantation,” Science Direct, July 10, 2006, www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0G-4K0FJWC-2&_user=10&_coverDate=07%2F10%2F2006&_alid=469379479&_rdoc=1&_fmt=summary&_orig=search&_cdi=4862&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersio n=0&_userid=10&md5=203dead71214575a7c9c0ff0390ae8c9
• “Pioneering steps for spine treatment,” Atlanta Business Chronicle, October 23, 2006, atlanta.bizjournals.com/atlanta/stories/2006/10/23/story6.html
• “The use of hemopoietic stem cells derived from human umbilical cord blood to promote restoration of spinal cord tissue and recovery of hindlimb function in adult rats,” Journal of Neurosurgery, Spine (JNAS), November 2006, www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=17120892&dopt=Abstract
• “Man walks, courtesy stem cell therapy,” The Tribune (India), February 25, 2007, www.tribuneindia.com/2007/20070226/main7.htm

WOUNDS/BURNS

• “Adult Stem Cells Can Reduce the Side Effects of Radiation Therapy,” FreeRepublic.com (Fresno, CA), October 9, 2006, www.freerepublic.com/focus/f-news/1716594/posts
• “IU doctors treating PAD with stem cells,” South Bend Tribune (Indiana), December 13, 2006, www.southbendtribune.com/apps/pbcs.dll/article?AID=/20061213/Lives08/612130449/- 1/LIVES05/CAT=Lives08
• “Aldagen Announces Texas Heart Institute as First Site in its Stem Cell Clinical Trial to Treat Critical Limb Ischemia,” Medical News Today, December 16, 2006, www.medicalnewstoday.com/printerfriendlynews.php?newsid=59182

We advise you to look up these articles and, if you want to print hard copies, do so immediately, as some may be available online for a short time only. If the link is no longer working, do an Internet search for the article, as it may be posted elsewhere.

Articles compiled by
Richard M. Doerflinger
Deputy Director of Pro-Life Activities
U.S. Conference of Catholic Bishops
3211 4th Street NE, Washington D.C.
20017 202-541-3070 / fax 202-541-3054 rdoerflinger@usccb.org