Will Artificial Ovaries Mean No More Menopause?

(MIT Technology Review) – During menopause a woman’s ovaries stop working—leading to hot flashes, sleep problems, weight gain, and worse, bone deterioration. Now scientists are exploring whether transplanting lab-made ovaries might stop those symptoms. In one of the first efforts … Read More

Early Embryos Kept in Check

(Nature) – During embryonic development, cells differentiate into particular lineages according to information about their position in the embryo. This adoption of a particular cellular identity often triggers changes in the organization of the embryo, which, in turn, results in … Read More

Stem Cells Meet AI in Quest to Mass-Produce Key Disease Fighters

(Bloomberg) – A half-century ago, Canadian scientists discovered transplantable stem cells, which can grow into any kind of human tissue. Now, a government-backed research facility in Toronto wants to create a partially automated factory that would mass-produce these human building … Read More

Gene Editing Is Now Outpacing Ethics

(Washington Post) – One practical solution is to bring the philosophy and ethics toolbox to the floor of the lab itself, to the point where the lines begin to be drawn in the first place. I’m a philosopher and ethicist … Read More

How Zika Virus Induces Congenital Microcephaly

(Medical Xpress) – Epidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex. However, the mechanism of … Read More

CRISPR Therapeutics Plans Its First Clinical Trial for Genetic Disease

(Wired) – In the end, Crispr’s leading luminaries formed three companies—Caribou Biosciences, Editas Medicine, and Crispr Therapeutics—to take what they had done in their labs and use it to cure human disease. For nearly five years the “big three’ Crispr … Read More

Grow Your Own: The Race to Create Body Parts in the Lab

(The Guardian) – The ultimate goal remains to make synthetic organs from scratch using a synthetic scaffold, as Macchiarini tried and failed to do with tracheas. Pig scaffolds do not pose a risk, but manufacturing them does not readily scale … Read More

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